1. Salerno AG, Wanschel ACBA, Dulce RA, Hatzistergos KE, Balkan W, Hare JM. S-nitrosoglutathione reductase (GSNOR) deficiency accelerates cardiomyocyte differentiation of induced pluripotent stem cells. J Cardiovasc Aging 2021;1:13.
2. Hatzistergos KE, Durante MA, Valasaki K, Wanschel CBA, Harbour JW, Hare JM. A novel cardiomyogenic role for Isl1+ neural crest cells in the inflow tract. Science Advances 2020, 6(49):eaba9950. PMID: 33268364 (Corresponding author).
3. Yousefi, K., Irion, CI, Takeuchi LM,, Ding W, Lambert G, Eisenberg T, Sukkar S, Granzier HL, Methawasin M., Lee DI, Hahn V, Kass, DA, Hatzistergos KE, Hare JM, Webster KA, Shehadeh LA. Osteopontin Promotes Left Ventricular Diastolic Dysfunction through a Mitochondrial Pathway in Alport (Col4a3-/-) Mice. J Am Coll Cardiol. 2019 Jun 4;73(21):2705-2718. PMID: 31146816
4. Hatzistergos KE, Williams AR, Dykxhoorn DM, Bellio MA, Yu W, Hare JM. Tumor Suppressors RB1 and CDKN2a Cooperatively Regulate Cell-Cycle Progression and Differentiation During Cardiomyocyte Development and Repair: Implications for Stimulating Neomyogenesis with Cell-Based Therapy. Circ Res. 2019 Apr 12;124(8):1184-1197. PMID: 30744497 (Corresponding author, Impact factor: 15.211).
5. Tompkins B, Rieger A, Florea V, Natsumeda M, Banerjee M, Nigh E, Landin AM, Rodriguez G, Hatzistergos KE, Schulman I, and Hare JM. Comparison of Mesenchymal Stem Cell Efficacy in Ischemic Versus Nonischemic Dilated Cardiomyopathy. J Am Heart Assoc. 2018 Jul 12;7(14). pii: e008460. PMID: 30005555
6. Bagno L, Hatzistergos KE, Balkan W, and Hare JM. Mesenchymal Stem Cell-Based Therapy for Cardiovascular Disease: Progress and Challenges. Mol Ther. 2018. 2018 May 25. pii: S1525-0016(18)30212-0. PMID: 29807782.
7. Asumda FZ, Hatzistergos KE, Jakubski S, Schiff ER, Thomas E. Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. Differentiation. 2018 Mar 27;101:16-24. PMID: 29626713.
8. Hatzistergos KE, Jiang Z, Valasaki K, Takeuchi LM, Balkan W, Atluri P, Saur D, Seidler B, Tsinoremas N, DiFede DL, Hare JM. Simulated Microgravity impairs cardiac autonomic neurogenesis from neural crest cells. Stem Cells Dev. 2018 Jan 16. PMID: 29336212.
9. Natsumeda M., Florea V, Rieger A, Tompkins BA, Banerjee MN, Golpanian S, Fritsch J, Landin AM, Kashikar ND, Karantalis V, Loescher VY, Hatzistergos KE, Bagno L, Sanina C, Mushtaq M, Rodriguez J, Rosado M, Collon K, Vincent L, Kanelidis AJ, Schulman IH, Mitrani R, Heldman AW, Balkan W, Hare JM. A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration. J Am Coll Cardiol. 2017 Nov 14;70(20):2504-2515. PMID: 29145950.
10. Chen X, Wang S, Xu H, Pereira JD, Hatzistergos KE, Saur D, Seidler B, Hare JM, Perrella MA, Yin Z, Liu X. Evidence for a retinal progenitor cell in the postnatal and adult mouse. Stem Cell Res. 2017 Aug;23:20-32. PMID: 28672156.
11. Hatzistergos KE, Vedenko A. Cardiac Cell Therapy 3.0: The beginning of the end or the end of the beginning? Circ Res. 2017 Jul 7;121(2):95-97. PMID: 28684618. (Corresponding author).
12. Hare JM, DiFede DL, Castellanos AM, Florea V, Landin AM, El-Khorazaty J, Khan A, Mushtaq M, Lowery MH, Byrnes JJ, Hendel RC, Cohen MG, Alfonso C, Valasaki K, Pujol MV, Gomes S, Fishman JE, Ghersin E, PattanyP, Golpanian S, Delgado C, Abuzeid F, Vidro-Casiano M, Premer C, Medina A, Porras V, Hatzistergos KE, Anderson E, Mendizabal A, Mitrani R, Heldman AW. Randomized Comparison of Allogeneic vs Autologous Mesenchymal Stem Cells in Patients with Non-lschemic Dilated Cardiomyopathy - The POSEIDON-DCM Trial. J Am Coll Cardiol. 2016 Nov 14. PMID: 27856208.
13. Kulandavelu S, Karantalis V, Fritsch J, Hatzistergos KE, Loescher VY, McCall F, Wang B, Bagno L, Golpanian S, Wolf A, Grenet J, Williams A, Kupin A, Rosenfeld A, Mohsin S, Sussman MA, Morales M, Balkan W, Hare JM. Pim1 Kinase Overexpression Enhances ckit+ Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. J Am Coll Cardiol. 2016 Dec 6;68(22):2454-2464. PMID: 27908351.
14. Bellio MA, Rodrigues CO, Landin AM, Hatzistergos KE, Florea V, Valasaki K, Khan A, Hare JM, Schulman IH. Physiologic and Hypoxic Oxygen Concentration Differentially Regulate Human c-Kit+ Cardiac Stem Cell Proliferation and Migration. Am J Physiol Heart Circ Physiol. 2016 Sep 30:ajpheart.00449.2016. (PMID: 27694215).
15. Hatzistergos KE, Saur D, Seidler B, Balkan W, Breton M, Valasaki K, Takeuchi LM, Landin AM, Khan A, Hare JM. Stimulatory effects of Mesenchymal Stem Cells on cKit+ Cardiac Progenitors are Mediated by SDF1/CXCR4 and SCF/cKit Signaling Pathways. [Circ Res. 2016 Sep 30;119(8):921-30]. PMID: 27481956 (Journal Cover).
16. Golpanian S, Wolf A, Hatzistergos KE, Hare JM. Rebuilding the Damaged Heart: Mesenchymal Stem Cells, Cell-based therapy and Engineered Heart Tissue. Physiol Rev. 2016 Jul;96(3):1127-68. PMID:27335447.
17. Hatzistergos KE, Hare JM. Murine models demonstrate distinct vasculogenic and cardiomyogenic cKit+ lineages in the heart. Circ. Res. 2016 Feb 5;118(3):382-7. PMID: 26846638.
18. Hatzistergos KE, Hare JM. Cell Therapy: Targeting Endogenous Repair Versus Remuscularization. Circ Res. 2015 Sep 25;117(8):659-61. PMID: 26405181.
19. Hatzistergos KE, Takeuchi LM, Saur D, Seidler B, Dymecki SM, Mai JJ, White IA, Balkan W, Kanashiro-Takeuchi RM, Schally AV, Hare JM. cKit+ cardiac progenitors of neural crest origin. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13051-6. PMID: 26438843.
20. Hatzistergos KE, Paulino EC, Dulce RA, Takeuchi LM, Bellio MA, Kulandavelu S, Cao Y, Balkan W, Kanashiro-Takeuchi RM, Hare JM. S-Nitrosoglutathione Reductase Deficiency Enhances the Proliferative Expansion of Adult Heart Progenitors and Myocytes Post Myocardial Infarction. J Am Heart Assoc. 2015 Jul 15;4(7). PMID: 26178404.
21. Karantalis V, Suncion-Loescher VY, Bagno L, Golpanian S, Wolf A, Sanina C, Premer C, Kanelidis AJ, McCall F, Wang B, Balkan W, Rodriguez J, Rosado M, Morales A, Hatzistergos K, Natsumeda M, Margitich I, Schulman IH, Gomes SA, Mushtaq M, DiFede DL, Fishman JE, Pattany P, Zambrano JP, Heldman AW, Hare JM. Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy. J Am Coll Cardiol. 2015 Nov 3;66(18):1990-9. PMID: 26516002.
22. D’Ippolito G, Gomez LA, Curtis KM, Delcroix GJR, Hare JM, Hatzistergos KE, Oskouei BN, Howard GA, Reiner T, Schiller PC. Isolation and Characterization of Swine MIAMI Cells: A Valuable Animal Model for Adult Stem Cell Therapy. CellR4. Jan 2014; 2(5).
23. Goldstein BJ, Goss GM, Hatzistergos KE, Rangel EB, Seidler B, Saur D, Hare JM. Adult c-Kit(+) progenitor cells are necessary for maintenance and regeneration of olfactory neurons. J Comp Neurol. 2015 Jan 1;523(1):15-31. PMID: 25044230.
24. Ramachandran S, Suguihara C, Drummond S, Chatzistergos K, Klim J, Torres E, Huang J, Hehre D, Rodrigues CO, McNiece IK, Hare JM, Young KC. Bone Marrow-Derived c-kit(+) Cells Attenuate Neonatal Hyperoxia-Induced Lung Injury. Cell Transplant. 2015;24(1):85-95. PMID: 23759597.
25. Grichnik JM, Ross AL, Schneider SL, Sanchez MI, Eller MS, Hatzistergos KE. How, and from which cell sources, do nevi really develop? Exp Dermatol. 2014 May;23(5):310-3. PMID: 24588745.
26. Williams AR, Hatzistergos KE, Addicott B, McCall F, Carvalho D, Suncion V, Morales AR, Da Silva J, Sussman MA, Heldman AW, Hare JM. Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarction. Circulation. 2013 Jan 15;127(2):213-23. PMID: 23224061.
27. Karantalis V, Balkan W, Schulman IH, Hatzistergos K, Hare JM. Cell-Based Therapy for Prevention and Reversal of Myocardial Remodeling. Am J Physiol Heart Circ Physiol. 2012; 303(3):256-270. PMID: 22636682.
28. Blum A, Gomes SA, Hatzistergos KE. Osteopontin Function and Interaction with Vascular Calcification and Atherosclerosis. J App. Med. Sci. Dec 2012; 1(2): 1-13.
29. Oskouei BN, Lamirault G, Joseph, C, Treuer AV, Landa S, Da Silva J, Hatzistergos KE, Dauer M, Balkan W, McNiece I and Hare JM. Increased Potency of Cardiac Stem Cells Compared with Bone Marrow Mesenchymal Stem Cells in Cardiac Repair. Stem Cells Trans Med. 2012 Feb 07 (Journal Cover, Inaugural Issue). PMID: 25044230.
30. Kanashiro-Takeuchi RM, Takeuchi LM, Rick FG, Dulce R, Treuer AV, Florea V, Rodrigues CO, Paulino EC, Hatzistergos KE, Selem SM, Gonzalez DR, Block NL, Schally AV, Hare JM. Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI). Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):559-63. PMID: 22203988.
31. Kanashiro-Takeuchi RM, Takeuchi LM, Hatzistergos KE, Quevedo H, Selem S, Treuer AV, Song Y, Hu Q, Hare JM. Effects of Combination of Proliferative Agents and Erythropoietin on Left Ventricular Remodeling Post-Myocardial Infarction. Clin. Transl. Sci. 2011 Jun;4(3):168-74. PMID: 21707946.
32. Hatzistergos KE, Blum A, Ince T, Grichnik JM, Hare JM. What is the oncologic risk of stem cell treatment for heart disease? Circ Res. 2011 May 27;108(11):1300-3. PMID: 21617132.
33. Hatzistergos KE, Hare JM. Response to Letter by Deng. Circ. Res., Nov 12, 2010; 107(10): e18 - e18.
34. Hatzistergos KE, Quevedo HC, Oskouei BN, Hu Q, Feigenbaum GS, Margitich IS, Mazhari R, Boyle A, Zambrano JP, Rodriguez JE, Dulce R, Pattany PM, Valdes D, Revilla C, Heldman AW, McNiece I, Hare JM. Bone Marrow Mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation. Circ Res. 2010 Oct 1;107(7):913-22. Epub 2010 Jul 29. PMID: 20671238.
35. Quevedo HC, Hatzistergos KE, Oskouei BN, Feigenbaum GS, Rodriguez JE, Valdes D, Pattany PM, Zambrano JP, Hu Q, McNiece I, Heldman AW, Hare JM. Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14022-7. Epub 2009 Aug 5. PMID: 19666564.
36. Schuleri KH, Feigenbaum GS, Centola M, Weiss ES, Zimmet JM, Turney J, Kellner J, Zviman MM, Hatzistergos KE, Detrick B, Conte JV, McNiece I, Steenbergen C, Lardo AC, Hare JM. Autologous mesenchymal stem cells produce reverse remodelling in chronic ischaemic cardiomyopathy. Eur Heart J. 2009 Jul 8. PMID: 19586959.
37. Schuleri KH, Amado LC, Boyle AJ, Centola M, Saliaris AP, Gutman MR, Hatzistergos KE, Oskouei BN, Zimmet JM, Young RG, Heldman AW, Lardo AC, Hare JM. Early improvement in cardiac tissue perfusion due to mesenchymal stem cells. Am J Physiol Heart Circ Physiol. 2008 May;294(5):H2002-11. PMID: 18310523.
38. Young KC, Torres E, Hatzistergos KE, Peng JH, Hehre D, Suguihara CY, Hare JM. Inhibition of the SDF-1/CXCR4 AXIS Attenuates neonatal Hypoxia-Induced Pulmonary hypertension. Circ Res. 2009 Jun 5;104(11):1293-301. PMID: 19423843.
39. Hatzistergos KE, Mitsi AC, Zachariou C, Skyrlas A, Kapatou E, Agelaki MG, Fotopoulos A, Kolettis TM, Malamou-Mitsi V. Randomised comparison of growth hormone versus IGF-1 on early post-myocardial infarction ventricular remodelling in rats. Growth Horm IGF Res. 2008 Apr;18(2):157-65. Epub 2007 Sep 21. PMID: 17889582.
40. Kolettis T, Vlahos AP, Louka M, Hatzistergos KE, Baltogiannis GG, Agelaki MM, Mitsi A, Malamou-Mitsi V. Characterisation of a rat model of pulmonary arterial hypertension. Hellenic J Cardiol. 2007 Jul-Aug;48(4):206-10. PMID: 17715611.
41. Mitsi AC*, Hatzistergos KE*., Niokou D., Pappa L., Baltogiannis G.G., Tsalikakis D.G., Papalois A., Kyriakides Z.S., Malamou-Mitsi V., Kolettis T.M. Early, intracoronary growth hormone administration attenuates ventricular remodeling in a porcine model of myocardial infarction. Growth Hormone & IGF Research 2006;16:93-100 (equal contribution of the first two authors). PMID: 16624608.
42. Baltogiannis GG, Tsalikakis DG, Mitsi AC, Hatzistergos KE, Elaiopoulos D, Fotiadis DI, Kyriakides ZS, Kolettis TM. Endothelin receptor-A blockade decreases ventricular arrhythmias after myocardial infarction in rats. Cardiovasc Res. 2005, 1;67(4):647-654. PMID: 15907816.
43. Mitsi AC, Hatzistergos K, Baltogiannis GG, Kolettis TM., Early, selective growth hormone administration may ameliorate left ventricular remodelling after myocardial infarction. Med Hypotheses. 2005;64(3):582-5. PMID: 15617872.
